If your symptoms or health problems do not get better or if they become worse, call your doctor. Taking more of this medicine (rizatriptan tablets) (a higher dose, more often) than your doctor told you to take may cause your headaches to become worse. Increased blood pressure can occur, and blood pressure should be monitored. commonly, these are "non-preferred" brand drugs. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Very bad and sometimes deadly heart problems like heart attack and a heartbeat that is not normal have rarely happened within a few hours This website also contains material copyrighted by 3rd parties. Either naratriptan 1 mg or zolmitriptan 2.5 mg dosed twice a day, or frovatriptan given with a starting dose of 10 mg, then 2.5 mg twice a day are typical regimens in the menstrual window that ⦠Fast Five Quiz: Migraine Prevention and Treatment, CGRP May Offer Both Migraine Treatment and Prevention. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9yZWZlcmVuY2UubWVkc2NhcGUuY29tL2RydWcvbWF4YWx0LW1heGFsdC1tbHQtcml6YXRyaXB0YW4tMzQzMDMz, View explanations for tiers and commonly, these are generic drugs. Tell your doctor if you are pregnant, plan on getting pregnant, or are breast-feeding. Seizures have been reported as has sexual dysfunction. Manage and view all your plans together – even plans in different states. Throw away unused or expired drugs. Acute treatment of migraine with or without aura, 5-10 mg PO at onset of symptoms; repeat dose after 2 hours if necessary; not to exceed 30 mg/24 hr, Patients taking propranolol: Limit dose to 5 mg PO and do not exceed 15 mg/24 hr, <6 years: Safety and efficacy not established, 6-17 years: (40 kg or greater): 10 mg PO once q24hr, Efficacy and safety of treatment with more than 1 dose within 24 hours in pediatric patients has not been established, 6-17 years (<40 kg) taking propranolol: Do not prescribe rizatriptan, 6-17 years (≥40 kg) taking propranolol: Limit dose to 5 mg PO once q24hr; not to exceed 5 mg/24hr, Pain/pressure in chest, neck, throat, jaw (<2%), Myocardial infarction and coronary artery vasospasm in patients with CAD risk factors, Ischemic heart disease, uncontrolled hypertension, or other significant cardiovascular disease, History of stroke or transient ischemic attack, Within 24 hours of another 5-HT1 agonist or ergot derivative, Use caution in hepatic/renal insufficiency, Overuse of acute migraine drugs (eg, ergotamine, triptans, opioids, or combination of these drugs for ≥10 days/month) may lead to exacerbation of headache (medication overuse headache), Coronary artery vasospasm, ventricular tachycardia/fibrillation, cardiac arrest, myocardial infarction, transient ischemia, and death reported with the use of 5-HT1 agonists, Cerebral/subarachnoid hemorrhage and stroke reported with the use of 5-HT1 agonists, Significant hypertension or hypertensive crisis reported in patients with and without history of hypertension, Not for use in the prevention of migraine or the treatment of cluster headaches, Maxalt-MLT tablets contain phenylalanine (not for use in patients with phenylketonuria), Patients with sensations of chest pain/pressure/tightness or symptoms suggestive of angina following dosing should be evaluated for coronary artery disease or Prinzmetal’s angina before administering additional doses; monitor with ECG if dosing is resumed and similar symptoms occur, Peripheral vascular ischemia and colonic ischemia, gastrointestinal ischemia/infarction, splenic infarction, and Raynaud’s syndrome reported with 5-HT1 agonist, Transient or permanent partial vision loss and blindness reported (rare), Not for administration to patients who have risk factors for coronary artery disease (CAD), including hypertension, obesity, hypercholesterolemia, diabetes, menopause, strong family history of CAD, male >40 years of age or is a smoker unless patient undergoes adequate cardiac evaluation; patients suspected of having CAD, should have CAD ruled out before considering use of drug; if evaluation satisfactory, first dose should be administered in the healthcare provider’s office; perform periodic evaluation of cardiovascular status in all patients, Available data in pregnant women are not sufficient to draw conclusions about drug-associated risk for major birth defects and miscarriage, The Pregnancy Registry for rizatriptan did not identify any pattern of congenital anomalies or other adverse birth outcomes over the period of 1998-2018; however, the lack of identification of any pattern should be viewed with caution, as the number of prospective reports with outcome information was low and did not provide sufficient power to detect an increased risk of individual birth defects associated with the use, Additionally, there was significant loss to follow-up in the prospective pregnancy reports, further complicating this assessment of an association between rizatriptan and any pattern of congenital anomalies or other adverse birth outcomes, Data are not available on the presence of rizatriptan or any active metabolites in human milk, or on the effects of rizatriptan on the breastfed infant, or on milk production, Rizatriptan was excreted in rat milk, with levels in milk ~6 times those in maternal plasma. 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